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Technical Review Article | Open Access | Published 8th October 2025 Current Developments In Microfluidic Platforms For Controlled Drug...

Depot injections represent a pivotal advancement in sustained and controlled drug delivery systems, offering prolonged therapeutic effects, enhanced patient compliance, and reduced dosing frequency. This review comprehensively examines the formulation strategies, mechanisms of drug release, clinical applications, and recent innovations in depot injection technologies. Polymeric matrices, lipid-based systems, and in situ forming depots are discussed alongside their pharmacokin

Neurodegenerative disorders, which include Alzheimer's, Parkinson's, and Huntington's, pose a significant worldwide health concern due to their gradual loss of neurons and cognitive impairment. The impermeability of the blood-brain barrier (BBB), the quick metabolism of medications, and non-specific delivery make traditional treatment approaches ineffective. Because they allow for site-specific drug administration, improve BBB penetration, and increase therapeutic efficacy wh