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Contamination control has moved from the sidelines to the spotlight in the pharmaceutical industry. As sterile drug manufacturing faces mounting regulatory expectations and rising product complexities, the call for zero tolerance towards contamination is louder than ever.

The aim of this study was to evaluate the efficacy of a UV-C disinfection robot intended for use on various cleanroom surfaces in the manufacturing facilities at AstraZeneca against a panel of different microorganisms. The studies performed used a method based on the Surface Challenge Test Method EN 13697² to evaluate the reduction in microbial viability after an inoculated surface was exposed to a with a light source emitting 254nm UV-C energy. In this surface challenge test

A multitude of measures are used to minimise contamination ingress into ‘cleaner’ cleanrooms, as presented by less clean areas. Airlocks serve a significant role in achieving this effect. However, for cleanrooms interfacing corridors, particularly in aseptic facilities, there are several vulnerabilities which need to be considered. These include the behavioural elements of personnel (walking speed and motion, numbers of people and so on) together with design factors including

Transdermal drug delivery systems provide a convenient and patient-friendly alternative to oral or injectable formulations by administering medication continuously through the skin. To address antibiotic resistance and poor oral compliance, a transdermal patch for azithromycin, a broad-spectrum macrolide antibiotic, could improve therapeutic outcomes¹⁻³.

EJPPS Volume 30, Issue 3 highlights advances in pharmaceutical science and cleanroom technology. Peer-reviewed papers explore bio-decontamination using VHP, UV disinfection robots, and maintenance optimization in CG membrane systems. Reviews cover microfluidics, depot injections, polysorbate stability, and nanocarriers for neurodegenerative diseases. Editorials discuss digitalization, contamination control, and current regulatory updates from July–September 2025.